Our group
3D Cancer Models
Nano-sized Therapeutic and Diagnostic Tools for Cancer
Cancer Microenvironment
3D Bioprinting
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Welcome to the
SATCHI-FAINARO LABORATORY

about us

Combining multidisciplinary basic, translational and clinical approaches for cancer therapy

In our lab, we invest multidisciplinary efforts to elucidate the basic molecular mechanisms responsible for cancer progression to an aggressive, metastatic, drug-resistant phenotype in order to reveal new “druggable targets” for clinical translation. To achieve this goal, we exploit a rich platform of cell lines, ex vivo 3D models and in vivo mouse models of cancer as well as fresh and archived tissue specimens obtained from fruitful collaborations with several of TAU’s affiliated hospitals. We use a range of molecular and functional techniques to identify and validate new markers and drivers of cancer progression. The newly-gained knowledge is harnessed for the design of novel clinically-relevant polymer-based diagnostic and therapeutic tools for cancer. Our vision is that our multidisciplinary approach will revolutionize our perception of tumor progression and consequently the way we diagnose and treat cancer.

Photo by: Eric Sultan (Lady Globes)

Ronit Satchi-Fainaro, Ph.D.

Head, Cancer Research and Nanomedicine Laboratory

Kurt and Herman Lion Chair in Nanosciences and Nanotechnologies

Head of the TAU Kahn 3D Printing Initiative

One of the seven collaborations between architects and biologists. Architectural Speculation: Urban Angiogenesis, Knafo Klimor Architects & Prof. Ronit Satchi-Fainaro, 2016. 

“New Revelations that Will Bring a Revolution” – a lecture in tribute of Bob Marley who died of cancer (in Hebrew)

“Nano GPS for personalized theranostics” – a lecture (in Hebrew) given as a part the Tel Aviv University event on the “White Night” that took place at Tel Aviv Port. 

RESEARCH HIGHLIGHTS

Our new paper in Advanced Therapeutics on targeted combination therapy for melanoma is out!

Rational Design of Polyglutamic Acid Delivering an Optimized Combination of Drugs Targeting Mutated BRAF and MEK in Melanoma

May 2020 | Advanced Therapeutics
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Immunization with mannosylated nanovaccines and inhibition of the immune-suppressing microenvironment sensitizes melanoma to immune checkpoint modulators

August 2019 | Nature Nanotechnology | doi: 10.1038/s41565-019-0512-0
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Image-Guided Surgery Using Near-Infrared Turn-On Fluorescent Nanoprobes for Precise Detection of Tumor Margins​​

May 2018 | Theranostics (8) 13, 3437-3460 ​​
Read the full article

Cover Feature

news and events

LaCaixa Impulse COVID-19 grant
LaCaixa Impulse COVID-19 grant May 2020
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The RSF lab is honored and happy to be awarded with the LaCaixa Impulse COVID-19 grant with Florindo Lab from Lisbon University.
NOFAR Incentive Program
NOFAR Incentive ProgramMay 2020
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The Satchi-Fainaro lab was awarded the NOFAR grant for applied academic research in Bio-technology and Nano-technology
Kadar Family Award for Outstanding Research
Kadar Family Award for Outstanding ResearchFebruary 2020
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Prof. Satchi-Fainaro was selected to receive the Kadar Family Award for Outstanding Research
20 Promising Israelis of the New Decade
20 Promising Israelis of the New DecadeJanuary 2020
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Prof. Satchi-Fainaro was selected to be inlcuded in "20 Promising Israelis of the New Decade" list of Yedioth Ahronoth, in the field of medicine
Friedrich Wilhelm Bessel Research Award​
Friedrich Wilhelm Bessel Research Award​December 2019
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Prof. Satchi-Fainaro was selected to receive the Friedrich Wilhelm Bessel Research Award from Alexander von Humboldt Foundation
Collaboration aggreement with TEVA
Collaboration aggreement with TEVANovember 2019
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Teva and Tel Aviv University sign a collaboration agreement for innovative R&D in the fields of cancer and brain studies
2018 Youdim Family Prize ​
2018 Youdim Family Prize ​October 2019
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Prof. Satchi-Fainaro was selected to receive the Youdim Family Prize for Excellence in Cancer Research
The vaccine that will beat skin cancer
The vaccine that will beat skin cancerOctober 2019
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Watch the full interview with Prof. Satchi-Fainaro on Channel 12 news
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Join Our Team!

Our lab is seeking for highly motivated and talented postdocs with background in cancer biology, chemistry or chemical engineering

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